Cosmetics & Dermatology
Featured Products
- Swine Skeletal Muscle Fibroblasts
- Swine Pancreatic Islets Cells
- Swine Lung Alveolar Cells
- Swine kidney Fibroblasts
- Swine Hepatocytes
- Swine Dermal Fibroblats
- Swine Cardiomyocytes
- Swine Cardiac Fibroblasts
- Rat Sprague Dolly Serum Wistar
- Rat Sprague Dolly Serum SD
- Rat Sprague Dolly Serum Immuno-deficient
- Rat Sprague Dolly Plasma Pooled Wistar
- Rat Sprague Dolly Plasma Pooled SD
- Rat Sprague Dolly Plasma Pooled Immuno-deficient
- Rat Sprague Dolly Plasma Female Immuno-deficient
- Rat Schwann Cells Wistar
- Rat Schwann Cells SD
- Rat Schwann Cells Immuno-deficient
- Rat Pulmonary Fibroblasts Wistar
- Rat Pulmonary Fibroblasts SD
- Rat Pulmonary Fibroblasts Immuno-deficient
- Rat Lymphatic Fibroblasts Wistar
- Rat Lymphatic Fibroblasts SD
- Rat Lymphatic Fibroblasts Immuno-deficient
- Rat IGS Serum Wistar
- Rat IGS Serum SD
- Rat IGS Serum SD
- Rat IGS Serum Immuno-deficient
- Rat IGS Plasma Wistar
- Rat IGS Plasma SD
- Rat IGS Plasma Pooled Wistar
- Rat IGS Plasma Pooled SD
- Rat IGS Plasma Pooled Immuno-deficient
- Rat IGS Plasma Immuno-deficient
- Rat Hepatocytes Suspension Wistar
- Rat Hepatocytes Suspension SD
- Rat Hepatocytes Suspension Immuno-deficient
- Rat Hepatocytes Plateable-Wistar
- Rat Hepatocytes Plateable-SD
- Rat Hepatocytes Plateable-Immuno-deficient
- Rat Cardiomyocytes Wistar
- Rat Cardiomyocytes SD
- Rat Cardiomyocytes Immuno-deficient
- Rat Cardiac Fibroblasts Wistar
- Rat Cardiac Fibroblasts SD
- Rat Cardiac Fibroblasts Immuno-deficient
- Rat Brain Vascular Pericytes Wistar
- Rat Brain Vascular Pericytes SD
- Rat Brain Vascular Pericytes Immuno-deficient
- Rat Bone Marrow Derived NK Cells Wistar
- Rat Bone Marrow Derived NK Cells Immuno-deficient
- Rat Bone Marrow Derived Muse Cells Wistar
- Rat Bone Marrow Derived Muse Cells SD
- Rat Bone Marrow Derived Muse Cells Immuno-deficient
- Rat Bone Marrow Derived Muse Cells
- Rat Bone Marrow Derived Mononuclear Cells Wistar
- Rat Bone Marrow Derived Mononuclear Cells Immuno-deficient
- Rat Bone Marrow Derived Mononuclear Cells
- Rat Bone Marrow Derived Mesenchymal Stem Cells Wistar
- Rat Bone Marrow Derived Mesenchymal Stem Cells Immuno Deficient
- Rat Bone Marrow Derived Mesenchymal Stem Cells CD
- Rat Bone Marrow Derived Dendritic Cells
- Rat Bone Marrow Derived Dendritic Cells
- Rat Bone Marrow Derived Dendritic Cells
- Primary Human Hepatic Stellate Cells
- 老鼠主要骨髓衍生CD1 NK细胞
- Mouse Primary Bone Marrow Derived NK Cells C57
- Mouse Plateable Hepatocytes (CD1)
- Mouse Plateable Hepatocytes (C57)
- Mouse Plateable Hepatocytes (BalbC)
- Mouse NOD SCID Plasma
- Mouse NOD SCID Lung Microsomes Mixed Gender
- Mouse NOD SCID Liver S9 Fraction Mixed Gender
- Mouse NOD SCID Liver Microsomes Mixed Gender
- Mouse NOD SCID Intestinal S9 Fraction Mixed Gender
- Mouse NOD SCID Intestinal Microsomes Mixed Gender
- Mouse NOD SCID Intestinal Cytosol Mixed Gender
- Mouse Muse cells CD1
- Mouse Muse cells C57
- Mouse Muse cells BalbC
- Mouse Lung S9 Fraction Mixed Gender
- Mouse Lung Microsomes Mixed Gender
- Mouse Lung Lysosomes Mixed Gender
- Mouse Lung Cytosol Mixed Gender
- Mouse Liver S9 Fraction Mixed Gender
- Mouse Liver Microsomes Mixed Gender
- Mouse Liver Microsomes Mixed Gender
- Mouse Liver Lysosomes Mixed Gender
- Mouse Liver Cytosol Mixed Gender
- Mouse Intestinal S9 Fraction Mixed Gender
- Mouse Intestinal Microsome Mixed Gender
- Mouse Intestinal Lysosomes Mixed Gender
- Mouse Intestinal Cytosol Mixed Gender
- Mouse Hybrid Plasma
- Mouse Hybrid Lung S9 Fraction Mixed Gender
- Mouse Hybrid Lung Microsomes Mixed Gender
- Mouse Hybrid Lung Lysosomes Mixed Gender
- Mouse Hybrid Lung Cytosol Mixed Gender
- Mouse Hybrid Liver S9 Fraction Mixed Gender
- Mouse Hybrid Liver Microsomes Mixed Gender
- Mouse Hybrid Liver Lysosomes Mixed Gender
- Mouse Hybrid Liver Cytosol Mixed Gender
- Mouse Hybrid Intestinal S9 Fraction Mixed Gender
- Mouse Hybrid Intestinal Microsomes Mixed Gender
- Mouse Hybrid Intestinal Lysosomes Mixed Gender
- Mouse Hybrid Intestinal Cytosol Mixed Gender
- Mouse Hepatocytes Suspension CD1
- Mouse Hepatocytes Suspension C57
- Mouse Hepatocytes Suspension BalbC
- Mouse Derived Mesenchymal Stem Cells
- Mouse Derived Dendritic Cells
- Mouse DBA S9 Fraction Mixed Gender
- Mouse DBA Plasma
- Mouse DBA Lung S9 Fraction Mixed Gender
- Mouse DBA Lung Microsomes Mixed Gender
- Mouse DBA Lung Lysosome Mixed Gender
- Mouse DBA Lung Cytosol Mixed Gender
- Mouse DBA Liver S9 Fraction Mixed Gender
- Mouse DBA Liver Lysosomes Mixed Gender
- Mouse DBA Liver Cytosol Mixed Gender
- Mouse DBA Intestinal Microsomes Mixed Gender
- Mouse DBA Intestinal Lysosomes Mixed Gender
- Mouse DBA Intestinal Cytosol Mixed Gender
- Mouse Cytosol Mixed Gender
- Mouse Cardiomyocytes CD1
- Mouse Cardiomyocytes C57
- Mouse Cardiomyocytes BalbC
- Mouse Cardiac Fibroblasts CD1
- Mouse Cardiac Fibroblasts C57
- Mouse Cardiac Fibroblasts BalbC
- Mouse C57 BL/6N Plasma
- Mouse C57 BL/6N Lung S9 Fraction Mixed Gender
- Mouse C57 BL/6N Lung Microsomes Mixed Gender
- Mouse C57 BL/6N Lung Lysosomes Mixed Gender
- Mouse C57 BL/6N Lung Cytosol Mixed Gender
- Mouse C57 BL/6N Liver S9 Fraction Mixed Gender
- Mouse C57 BL/6N Liver Microsomes Mixed Gender
- Mouse C57 BL/6N Liver Lysosomes Mixed Gender
- Mouse C57 BL/6N Liver Cytosol Mixed Gender
- Mouse C57 BL/6N Intestinal S9 Fraction Mixed Gender
- Mouse C57 BL/6N Intestinal Microsomes Mixed Gender
- Mouse C57 BL/6N Intestinal Lysosomes Mixed Gender
- Mouse Brain Vascular Pericytes
- 人类脐带血液引出ed NK cells
- 人类脐带血液引出ed Mononuclear cells
- 人类脐带血液引出ed Dendritic Cells
- 人类脐带血液引出ed CD34+ Cells
- Human T Helper Cells
- Human Splenic Fibroblasts
- Human Splenic Endothelial Cells
- Human Skin S9 Fraction Mixed Gender
- Human Skin Derived Microvascular Dermal Endothelial Cells Adult
- Human Skin Derived Epidermal Melanocytes Fetal
- Human Skin Derived Epidermal Melanocytes Adult
- Human Skin Derived Epidermal Keratinocytes Neonatal
- Human Skin Derived Epidermal Keratinocytes Fetal
- Human Skin Derived Epidermal Keratinocytes Adult
- Human Skin Derived Dermal Fibroblasts Fetal
- Human Skin Derived Dermal Fibroblasts Adult
- Human Serum Peripheral Blood Single Donor
- Human Serum Cord Blood Single Donor
- Human Serum Bone Marrow Single Donor
- Human Seminal vesicles microvascular endothelial cells
- Human Seminal Vesicles Fibroblasts
- Human Seminal Vesicles Endothelial cells
- Human S9 Fraction Heart
- Human S9 Fraction
- Human Pulmonary Small Airway Epithelial Cells
- Human Pulmonary Fibroblasts
- Human Pleatable Hepatocytes Pooled
- Human Plateable Hepatocytes
- Human Plasma Cord Blood Pooled
- Human Plasma
- Human Peripheral Blood-Derived NK Cells
- Human Peripheral Blood-Derived Muse Cells
- Human Peripheral Blood-Derived Mononuclear Cells
- Human Peripheral Blood-Derived Monocytes
- Human Peripheral Blood-Derived Mesenchymal Stem Cells
- Human Peripheral Blood-Derived Cytotoxic T-Cells
- Human Pericardial Fibroblasts
- Human Ovarian Surface Epithelial Cells
- Human Ovarian Fibroblasts
- Human Muse cells
- Human Microvascular Endothelial Cells
- Human Mammary Smooth Muscle Cells
- Human Mammary Fibroblasts
- Human Mammary epithelial cells
- Human Lung S9 Fraction Mixed Gender
- Human Lung Microsomes Mixed Gender
- Human Liver S9 Fraction Mixed Gender
- Human Liver Microsomes Mixed Gender
- Human Liver Microsomes
- Human Kidney Fibroblasts
- Human Islet Beta Cells
- Human Intestine Microsomes Pooled Mixed Gender
- Human Intestinal S9 Fraction Mixed Gender
- Human Hepatocytes in Suspension
- Human Eye Derived Limbal Fibroblasts
- Human Extra Embryonic Fetal Tissues Derived Mesenchymal Stem Cells
- Human Extra Embryonic Fetal Tissues Derived CD34 Positive Cells
- Human Endometrial Epithelial Cells
- Human Dental Pulp Derived Mesenchymal stem cells
- Human Dental Pulp Derived Gingival Fibroblasts
- Human Cytotoxic T Cells
- Human Cardiomyocytes
- Human Cardiac Fibroblasts
- Human Bronchial Fibroblasts
- Human Bone Marrow-Derived NK Cells
- Human Bone Marrow-Derived Mononuclear cells
- Human Bone Marrow-Derived Mesenchymal Stem Cells
- Human Bone Marrow-Derived Dendritic cells
- Human Bone Marrow-Derived CD 34 positive cells
- 人主动脉平滑肌细胞
- Human Aortic Endothelial Cells
- Human Adipose Tissue-Derived Stromal Vascular Fraction
- Human Adipose Tissue-Derived Preadipocytes
- Human Adipose Tissue derived Mesenchymal Stem cells
Drop your Query
Cell-based Testing:
Future-proof your lab today!
With the technological advancements in cell culture, the industry is moving towards cruelty-free research, wherein animals are no longer used for cosmetic development and testing. While regulatory authorities are also not in favor of animal testing in the first instance, the global cosmetic formulation is slowly shifting towards primary cells isolated from human tissues; as cardinal models for cosmetic testing.
- Primary Human Skin Fibroblasts
- Primary Human Keratinocytes
- Primary Human Melanocytes
- Primary Human Vaginal Epithelial Cells
- Primary Human Skin Epithelial Cells
- Balb/c 3T3 Mouse Fibroblast cell line
- 脂肪Tissue derived exosomes
- Skin Tissue derived exosomes
- Complete growth medium for fibroblasts
- Complete growth medium for keratinocytes/melanocytes
Phototoxicity
The dermal phototoxicity of active ingredients in cosmeceutical products is defined as the toxic response, elicited after exposure to primary skin models with the product. Several validation studies have demonstrated how the phototoxic potential of active ingredients can be assessed using various in vitro methods.
If a particular active ingredient is absorbing more UV light or visible light, it is very important to assess, whether this extensive absorption is causing any toxic effects when intended for human use. So far, various studies have been performed using immortalized mouse fibroblast cell lines Balb/c 3T3. However, using certain primary cells like keratinocytes, melanocytes, etc. various skin models can be reconstructed at different stages of maturity. These models were found to be histologically similar to that of in vivo human epidermis. The models can be further studied for specific differentiation markers like loricrin, keratin 10, keratin 5, etc.; along with some dermal/epidermal skin markers, such as Type IV collagen, laminin V, etc.
Accordingly, various other models can be prepared, such as:
- Skin irritation model
- Photoprotection model
- Skin corrosion model